Tocilizumab (anti-IL-6R)

Product Name：Tocilizumab

CAS No.:   375823-41-9                               

Formula:   C₆₄₂₈H₉₉₇₆N₁₇₂₀O₂₀₁₈S₄₂                          

Molecular Weight：  148 kDa                  

Type:      Whole antibody                   

Target：  IL-6 receptor
Antibody Form:  Purified immunoglobulin
Physical Form:  Solution
Storage:  -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light.
Description

ACTEMRA (Tocilizumab) is a recombinant humanized anti-human interleukin 6 (IL-6) receptor monoclonal antibody of the immunoglobulin IgG1κ (gamma 1, kappa) subclass with a typical H2L2 polypeptide structure. Each light chain and heavy chain consists of 214 and 448 amino acids, respectively. The four polypeptide chains are linked intra- and inter-molecularly by disulfide bonds. Tocilizumab has a molecular weight of approximately 148 kDa. The antibody is produced in mammalian (Chinese hamster ovary) cells.

Biological Activity
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
For research use only.Not for use in human