Secukinumab (anti-IL-17A)

Product Name：Secukinumab

CAS No.:     875356-43-7                            

Formula:    C₆₅₈₄H₁₀₁₃₄N₁₇₅₄O₂₀₄₂S₄₄                         

Molecular Weight：     151 kDa               

Type:      Whole antibody                  

Target：  IL17A
Antibody Form:  Purified immunoglobulin
Physical Form:   Solution
Storage:  -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light.
Description

Cosentyx (Secukinumab)is a recombinant human monoclonal IgG1/κ antibody that binds specifically to IL-17A. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line. Secukinumab has a molecular mass of approximately 151 kDa; both heavy chains of secukinumab contain oligosaccharide chains

Biological Activity
Secukinumab (anti-IL-17A) (Cosentyx, AIN457) is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A, and is applied for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis

For research use only. Not for use in humans