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Ranibizumab (Anti-VEGFA)

Item No.: 347396-82-1
SEC-HPLC>95%
Description
Description

Product NameRanibizumab

CAS No.:  347396-82-1                               

Formula:   C2158H3282N562O681S12                        

Molecular Weight48 kDa                    

Type:    Fab fragment                     

TargetVEGF-A
Antibody Form: Purified immunoglobulin
Physical Form:  Solution
Storage: -70±15 for long-term storage, 2-8 for short-term storage, away from light.

Description
LUCENTIS® (ranibizumab) is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment designed for intraocular use. Ranibizumab binds to and inhibits the biologic activity of human vascular endothelial growth factor A (VEGF-A). Ranibizumab, which lacks an Fc region, has a molecular weight of approximately 48 kilodaltons and is produced by CHO expression system.


Biological Activity
Ranibizumab (Anti-VEGFA) is a recombinant humanized IgG1 monoclonal antibody fragment that inhibits (VEGF-A) and degrades angiogenesis throughout the body and in the eye also interrupts the interaction of VEGF with its receptors, and thus prevents the subsequent growth of new blood vessels.

For research use only.Not for use in humans

 
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