Ramucirumab (anti-VEGFR2)

Product Name：Ramucirumab

CAS No.:   947687-13-0                              

Formula:    C₆₃₇₄H₉₈₆₄N₁₆₉₂O₁₉₉₆S₄₆                         

Molecular Weight：  147 kDa                  

Type:    Whole antibody                    

Target： VEGFR2 (KDR)
Antibody Form:  Purified immunoglobulin
Physical Form:  Solution
Storage:  -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light.
Description

CYRAMZA (ramucirumab) is a recombinant human IgG1 monoclonal antibody that specifically binds to vascular endothelial growth factor receptor 2. ramucirumab has an approximate molecular weight of 147 kDa. ramucirumab is produced in genetically engineered mammalian CHO cells

Biological Activity
Ramucirumab is a monoclonal antibody of the IgG1 class that binds to VEGF-R2 and prevents its activation. The IC50 value for blocking KDR binding to VEGF is 0.8 nM for ramucirumab

For research use only. Not for use in humans