Cetuximab (anti-EGFR)

Product Name：Cetuximab biosimilar

CAS No.:   205923-56-4                            

Formula:  C₆₄₈₄H₁₀₀₄₂N₁₇₃₂O₂₀₂₃S₃₆                           

Molecular Weight：  152 kDa                 

Type:    Whole antibody                     

Target： EGF receptor
Antibody Form:  Purified immunoglobulin
Physical Form:  Solution
Storage:  -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light.
Description

Cetuximab biosimilar is a recombinant, human/mouse chimeric monoclonal antibody that binds specifically to the extracellular domain of the human epidermal growth factor receptor (EGFR). Cetuximab biosimilar is composed of the Fv regions of a murine anti-EGFR antibody with human IgG1 heavy and kappa light chain constant regions and has an approximate molecular weight of 152 kDa. Cetuximab biosimilar is produced in mammalian (Chinese Hamster Ovary) cell culture. 

Biological Activity
Cetuximab, a novel molecular-targeted agent,is an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation.

For research use only.Not for use in humans