Alemtuzumab (Anti-CD52)

Product Name： Alemtuzumab biosimilar

CAS No.:     216503-57-0                            

Formula:    C₆₄₆₈H₁₀₀₆₆N₁₇₃₂O₂₀₀₅S₄₀                         

Molecular Weight：   150 kDa                 

Type:    Whole antibody                     

Target： CD52
Antibody Form:  Purified immunoglobulin
Physical Form:   Solution
Storage:  -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light.

Description

Alemtuzumab biosimilar is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) directed against the 21-28 kD cell surface glycoprotein, CD52,  is an IgG1 kappa antibody with human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody. The alemtuzumab biosimilar has an approximate molecular weight of 150 kD and  is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium.

Biological Activity
Alemtuzumab (Anti-CD52) is a humanized monoclonal antibody targeting against CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes

For research use only. Not for use in humans